Hormonal changes during pregnancy can significantly affect skin sensitivity, pigmentation, oil production and hydration levels. At the same time, research shows that certain skincare ingredients can be absorbed through the skin and enter the bloodstream, raising concerns about potential effects on foetal development[1].
For this reason, dermatologists commonly advise expectant mothers to carefully review their skincare routines and be aware of skin care ingredients to avoid during pregnancy, particularly those linked to hormonal disruption, developmental toxicity, or high levels of systemic absorption.
Below are some of the most commonly flagged skincare ingredients that expectant mothers should approach with caution.
Ingredient Category | Examples |
Retinoids (Vitamin A derivatives) | Retinol, Tretinoin, Adapalene, Retinyl Palmitate, Isotretinoin |
Hydroquinone & Arbutin | Hydroquinone, Alpha-Arbutin |
Salicylic Acid (High concentrations) | High-strength BHA, chemical peels |
Chemical Sunscreen Filters | Oxybenzone, Avobenzone, Octocrylene, Homosalate |
Hormone-Disrupting Preservatives | Parabens, Phthalates, Formaldehyde-releasing agents |
1. Retinoids (Vitamin A Derivatives)
Retinoids are among the most frequently highlighted ingredients to avoid. These include retinol, tretinoin, adapalene, retinyl palmitate and isotretinoin, whether in prescription or cosmetic products. They’re widely used for acne treatment and anti‑ageing.
Why avoid them? Retinoids taken orally are linked to serious birth defects and adverse pregnancy outcomes[2]. While topical use absorbs less, many dermatologists advise avoiding all forms to reduce any risk[3].
- Common sources: Anti‑ageing serums, acne products, prescription creams.
- Safer alternatives: Ingredients such as bakuchiol (a plant‑based alternative) are often recommended as pregnancy‑friendly retinol alternatives, but always check with your obstetrician first.
2. Hydroquinone and Arbutin
Hydroquinone is a powerful skin‑lightening agent frequently used to treat melasma and dark spots. It’s absorbed through the skin in relatively high amounts[1], which is why it’s not recommended during pregnancy.
Arbutin and alpha‑arbutin, often found in brightening products, can break down into hydroquinone on the skin, meaning they’re also best avoided.
- Common sources: Pigment‑correcting creams and serums.
- Safer alternatives: Vitamin C serums, niacinamide and azelaic acid can help with pigmentation concerns and are generally considered safer choices during pregnancy.
>> Little Étoile Mothers’ Care Radiant Clarity Serum helps improve the look of dull or uneven skin tone.
3. Salicylic Acid (High Concentrations)
Salicylic acid, a beta‑hydroxy acid (BHA), is widely used in acne treatments and exfoliants. While low concentrations (≤2%) in cleansers or rinse‑off products are often considered acceptable by dermatologists, higher concentrations and chemical peels should be avoided.
At higher strengths or when applied frequently over large areas of skin, salicylic acid can be absorbed into the bloodstream, increasing the potential for unwanted effects during pregnancy.
- Common sources: Chemical exfoliants, peels and some acne spot treatments.
- Safer alternatives: Azelaic acid or low‑strength glycolic acid (AHA) products, when used under medical guidance.
>> Learn more about salicylic acid usage during pregnancy.
4. Chemical Sunscreens (Certain Filters)
Chemical sunscreens contain UV‑absorbing compounds like oxybenzone, avobenzone, octocrylene and homosalate. These can act as endocrine disruptors[4] and may reach the bloodstream after regular use.
- Common sources: Everyday SPF products labelled “broad spectrum”.
- Safer alternatives: Mineral sunscreens with zinc oxide and titanium dioxide[4], which sit on the skin’s surface and are generally recommended during pregnancy.
>> The difference between mineral and chemical sunscreens
5. Parabens, Phthalates & Formaldehyde‑Releasing Preservatives
These ingredients are often used as preservatives or stabilisers in cosmetics. They may interfere with hormone function or reproductive health.
Why avoid them?
- Parabens can mimic oestrogen and may affect the endocrine system[5].
- Phthalates are linked to developmental and reproductive concerns[6].
- Formaldehyde‑releasing agents can be irritating or harmful with repeated exposure[7].
Common sources: Lotions, makeup, perfume, nail polish, hair products.
General Advice for Pregnant Women
- Consult your doctor: Dermatologists can provide personalised advice based on your health and pregnancy.
- Read labels carefully: Be diligent in checking ingredient lists. When in doubt, err on the side of caution.
- Patch test new products: Even seemingly safe ingredients can cause irritation during pregnancy due to hormonal changes.
- Keep it simple: During pregnancy, a minimalist approach to skincare can often be the best. Focus on gentle cleansers, moisturisers, and mineral sunscreens.
When to See a Doctor
Contact your dermatologist or obstetrician if you notice:
- Severe acne breakouts that do not respond to mild treatments.
- Rapidly changing moles or unusual pigmentation.
- Signs of skin infection (redness, swelling, pus).
- Any irritation, rash, or allergic reactions from skincare products.
Early consultation ensures that both you and your baby stay safe while managing your skincare needs.
FAQs
1. Can I use retinol or prescription retinoids during pregnancy?
No. Retinoids, including retinol, tretinoin, adapalene, and isotretinoin, are strongly advised against during pregnancy due to their association with birth defects and adverse pregnancy outcomes. Even topical forms are often avoided as a precaution. Safer alternatives include plant-based options like bakuchiol, but always consult your obstetrician first.
For closely related guidance, read our article: Is Niacinamide Safe During Pregnancy? Myths vs Facts.
2. What about salicylic acid or other exfoliants?
Low concentrations of salicylic acid (≤2%) in cleansers or rinse-off products are usually considered safe. However, high-strength chemical peels or leave-on acne treatments containing salicylic acid should be avoided. Safer alternatives include azelaic acid or low-strength glycolic acid under medical supervision.
3. Is it safe to use moisturisers and cleansers during pregnancy?
Yes. Gentle, fragrance-free cleansers and moisturisers are generally safe. A simple skincare routine focusing on hydration and protection with mineral sunscreen is recommended.
>> Explore Little Étoile Mothers’ Care Hydra-Lock Serum that delivers lasting hydration and comfort
4. Is it safe to use skincare products while breastfeeding?
Yes, many skincare ingredients that are safe during pregnancy are also considered safe while breastfeeding. However, products should not be applied directly to the nipples to avoid any risk to the baby.
>> The Little Étoile Mothers’ Care range is formulated to be safe for use during both pregnancy and the postpartum period.
5. Should I stop using all makeup products?
Not necessarily. Avoid products with parabens, phthalates, and formaldehyde-releasing preservatives. Look for pregnancy-safe or clean beauty makeup brands and patch test new products.
Further reading: Essential nutrients and vitamins for pregnancy
Reference
- Novitasari, A., et al. (2025). Exploring Safe and Harmful Skincare Ingredients in Pregnancy: An Umbrella Review. Media Penelitian dan Pengembangan Kesehatan, 35(3), 1190–1200. https://doi.org/10.34011/jmp2k.v35i3.3108
- Whelan, C. (2022, June 30). Can Using Products with Retinol Affect Pregnancy? Healthline. https://www.healthline.com/health/pregnancy/retinol-pregnancy
- Schleehauf, B. (2024). Dermatologist-approved pregnancy skin care. American Academy of Dermatology (AAD). https://www.aad.org/pregnancy-skin-care
- Bradley, S. (2024, July 2). Skin-Care Ingredients to Avoid During Pregnancy. The Bump. https://www.thebump.com/safe-skincare-pregnancy
- Breast Cancer Prevention Partners (BCPP). (2019). Parabens. BCPP.org. https://www.bcpp.org/resource/parabens/
- Almeida-Toledano, L., et al. (2024). Effect of prenatal phthalate exposure on fetal development and maternal/neonatal health consequences: A systematic review. The Science of the Total Environment, 950, 175080. https://doi.org/10.1016/j.scitotenv.2024.175080
- Agency for Toxic Substances and Disease Registry (ATSDR). (2014, October 21). Formaldehyde | Medical Management Guidelines. Toxic Substance Portal | CDC. https://wwwn.cdc.gov/formaldehyde-guidelines
Disclaimer: This guide is for informational purposes only and should not be used to diagnose health conditions or make changes to medical treatments. Always consult with your healthcare professional for advice.












